What is the success rate of ECT for treatment-resistant depression? (2024)

What is the success rate of ECT for treatment-resistant depression?

Electroconvulsive therapy (ECT) is considered the most effective short-term treatment for patients with severe or treatment-resistant depression, with 70–90% of patients showing improvement [2]. ECT involves the application of electricity to the scalp in order to induce seizure activity [3].

(Video) Ketamine vs. ECT for Major Depression | NEJM
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What is the effectiveness rate of ECT?

ECT is an effective medical treatment option, helping as many as 80-85 percent of patients who receive it. Most patients remain well for many months afterwards. The tendency to relapse after a favorable treatment outcome can often be countered by medication after a series of treatments.

(Video) What are the Success Rates of ECT?
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What is the response rate of ECT for depression?

Main findings. In this large, nationwide study of patients treated with ECT for unipolar, non-psychotic depression, we found high response rates in both groups, with 65.9% of patients with TRD assessed as much or very much improved after treatment, compared with 75.9% of patients with non-TRD.

(Video) Cheryl Overcomes Depression with Electroconvulsive Therapy
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Is ECT 100% effective?

Clinical evidence indicates that for individuals with uncomplicated, but severe major depression, ECT will produce substantial improvement in approximately 80 percent of patients. It is also used for other severe mental illnesses, such as bipolar disorder and schizophrenia.

(Video) Ketamine found to be at least as effective as ECT for treating major depression
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Does ECT work for treatment-resistant depression?

ECT is the most effective treatment available for severe and treatment-resistant depression, but it requires anesthesia and can cause side effects like memory loss,” says Irving Michael Reti, M.B.B.S., M.D., director of the Brain Stimulation Program and associate professor of psychiatry and behavioral sciences at the ...

(Video) Treatment Resistant Depression
What happens if ECT doesn't work for depression?

If ECT doesn't work to resolve symptoms, your doctor may recommend trying other brain stimulation techniques, such as: repetitive transcranial magnetic stimulation (rTMS) vagus nerve stimulation (VNS) deep brain stimulation.

(Video) ECT for Depression Patient Success Story
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What is the best predictor of the success of ECT?

Psychosis is perhaps the best-established predictor of ECT response. More than a dozen studies, from the 1950s to the recent Consortium for Research in ECT (CORE) multicenter study, show better response rates for this severe form of depression, in which delusions, paranoia, or both are present.

(Video) Dr. Syl Explains How Electroconvulsive Therapy (ECT) Works
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When should ECT not be used?

Given the potential risks involved, ECT should not be used if you have: Mild or moderate depression. Certain cardiovascular conditions, such as heart attacks, severe hypertension, recent heart attacks or strokes. A history of adverse reactions to anesthesia.

(Video) ECT Therapy for Severe Depression
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Are ECT results permanent?

Most people who undergo ECT have temporary memory loss and confusion. Most people's confusion clears up quickly, and memory loss usually goes away entirely within a few months. However, some people do have permanent memory problems.

(Video) Treating Treatment Resistant Depression
What condition has the best response to ECT?

ECT is the most effective treatment for biological depression and in many cases, the more severe the depression, the more likely it is that ECT will work. Response rates for an uncomplicated depression can be as high as 90%.

(Video) Who Benefits Most From ECT?
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What is the relapse rate after ECT?

After successful ECT, high relapse rates are observed. A meta-analysis showed that, despite continuation pharmacotherapy, 51% of patients relapsed within 12 months following successful ECT, with the majority relapsing within the first 6 months.

(Video) ECT - Caroline's story - How Electroconvulsive Therapy saved my life
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What are the statistics on ECT?

Those studies revealed a death rate of 2.4 per 100,000 treatments within 1 day of ECT in Texas (Dennis et al., 2017), mortality rates of less than 0.4 (day of ECT), 1.0 (up to 7 days post-treatment), respectively, 2.4 (up to 30 days post-treatment) per 10,000 ECTs in Canada, and less than 1 death per 73,440 treatments ...

What is the success rate of ECT for treatment-resistant depression? (2024)
Who is not a good candidate for ECT?

For example, children under age eleven cannot undergo ECT for mental health disorders. People with heart conditions and people who cannot handle short-acting sedatives or muscle relaxers should not undergo ECT treatments. In pregnant patients, ECT does not pose any serious risk to the fetus, or the expectant mother.

How many times can ECT be done?

People undergoing ECT need multiple treatments. The number needed to successfully treat severe depression can range from 4 to 20, but most people need a total of 6 to 12 treatments. The treatments are usually given three times a week — Monday, Wednesday, and Friday.

What is the conclusion of ECT?

CONCLUSION. ECT is an effective treatment for treatment-resistant depression and may be more effective than additional pharmacological strategies when patients haven't responded to several pharmacological interventions.

Is there a treatment for resistant depression?

If medications and psychotherapy aren't working, you may want to talk to a psychiatrist about additional treatment options: Repetitive transcranial magnetic stimulation (rTMS). This type of treatment uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression.

Can you fail ECT?

What happens if I fail my ECT induction? You only have one chance to pass your ECT induction and anyone who fails will not be permitted to retake it or work in a relevant school. Anyone failing will be dismissed from their post.

Which two disorders has ECT consistently showed its effectiveness?

Electroconvulsive therapy (ECT) is a safe and effective treatment for major depressive disorder, bipolar disorder, catatonia, schizophrenia, and several other conditions.

Does ECT have a high relapse rate?

In a systematic review and meta-analysis1 of modern era studies in which patients received continuation pharmacotherapy after a successful course of ECT, the cumulative relapse rates after stopping ECT were 27.1% at 3 months (11 studies; 95% confidence interval [CI], 0.21%–0.35%), 37.7% at 6 months (17 studies; 95% CI, ...

Is ECT more effective than antidepressants?

However, most patients who were resistant to antidepressant or psychotherapy showed improvement after ECT was introduced. In other words, ECT may have a greater effect than the two routinely used methods in fighting depression (Husain et al., 2004; Spaans et al., 2015; Liang et al., 2017, 2018).

What is the most serious side effect of ECT?

It can sometimes cause memory loss. This can be short-term. But some people experience long-term memory loss. Some people are offered ECT without being offered other treatments first, such as talking therapies for depression.

Why does ECT have a bad reputation?

The main source of continuing controversy concerns a possible adverse effect: memory loss. There is no question that ECT causes some memory loss, particularly of events near the time of the treatment. These memories often return, however.

Why ECT should be banned?

In fact, there is considerable evidence that ECT causes significant and irreversible brain damage. The human brain is a highly intricate organ, controlling the body with more than five trillion signals every second. It performs that feat with nearly eight times less than the power of a watch battery.

What percentage of people lose memory with ECT?

Recent studies of patients' perceptions of memory impairment after ECT are notable. Rose and colleagues25 summarized the results of 7 studies reporting on perceived memory loss and found that between 29% and 55% of respondents believed they experienced long-lasting or permanent memory changes.

Does ECT change personality?

Some people experience longer term memory loss, and difficulty making new memories. But some people do say after ECT they experience brain damage, a change in their personality, a loss of creativity, a lack of energy or drive, or lack of emotions.


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